Since the first report of the coronavirus in November 2019, the degree of COVID-19 infection has continued to this day, repeating its spread and mitigation. In the early days of the COVID-19 Pandemic, it was expected to be alleviated in the summer due to the nature of the existing respiratory virus, but the spread of COVID-19 was prolonged due to the continuous emergence of mutant viruses. Since then, vaccines have been developed, but short efficacy periods and cases of vaccine breakthrough infections have increased, making it necessary to consider the response of the With Corona era rather than countermeasures after the end.